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ABSTRACT INFORMATION
Title: 'Hearing Loss in Children with Congenital Cytomegalovirus (CMV) Infection: Findings of Houston Congenital CMV Longitudinal Study'
Track: 2 - Audiological Services
Keyword(s): Congenital CMV infection, cytomegalovirus, sensorineural hearing loss, longitudinal CMV study
Learning Objectives:
  1. describe the incidence of hearing loss in a longitudinal study of a cohort of CMV positive children with >10 years of follow-up
  2. describe the characteristics of the sensorineural hearing loss pattern among children with congenital CMV infection over a >10-yr period
  3. describe the type of audiologic testing used in this longitudinal study

Abstract:

An estimated 15-20% of cases of bilateral moderate to profound sensorineural hearing loss (SNHL) are attributable to congenital CMV infection. Approximately half of the identified hearing loss cases due to congenital CMV infection are late-onset or progressive. Consequently they are not often detected at birth through newborn hearing screening. We will describe a longitudinal study of 186 infants enrolled in the Houston Congenital CMV Longitudinal Study with more than 10 years of follow-up. Most CMV longitudinal studies are 4 to 5 years long. This study is unique because of the long follow up duration of >10 years. The presentation will report types of data collected, incidence of hearing loss, age of onset, and hearing loss pattern over the study period.
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Handouts: Handout is not Available
PRESENTER(S) / AUTHOR(S) INFORMATION
Stephanie Bialek - Author
CDC
     Credentials: MD, MPH
      Dr. Stephanie Bialek, MD, MPH is the Herpesvirus Team Lead in the Epidemiology Branch of the Division of Viral Diseases at the U.S. Centers for Disease Control and Prevention (CDC). She oversees epidemiologists who conduct studies of varicella, herpes zoster, and congenital cytomegalovirus (CMV), develop and evaluate strategies to prevent congenital CMV, monitor the impact of the varicella and zoster vaccination programs in the United States, and guide national policy on the use of these vaccines.
      ASHA DISCLOSURE:

Financial - No relevant financial relationship exist.

Nonfinancial - No relevant nonfinancial relationship exist.
Winnie Chung - Primary Presenter
Centers for Disease Control & Prevention
     Credentials: Au.D
      Winnie Chung, Au.D, a Health Scientist with CDC, is the subject matter expert with the Early Hearing Detection & Intervention (EHDI) team. Winnie Chung has been an audiology provider in various clinical setting from 1990 to 2009. She began her involvement in EHDI in 2001 providing outpatient hearing screening and diagnostic for newborns at Kaiser Permanente San Francisco and Oakland. From 2004 to 2009, besides coordinating Rhode Island state newborn hearing screening program, she also provided audiological services in the tertiary neonatal intensive care unit and managed the audiology outpatient clinic at Woman & Infants' Hospital. She joined CDC as a health scientist in April of 2009 providing technical assistance to state EHDI programs and investigating public health related issues for the CDC-EHDI team.
      ASHA DISCLOSURE:

Financial - No relevant financial relationship exist.

Nonfinancial - No relevant nonfinancial relationship exist.
Gail Demmler - Co-Presenter
Baylor School of Medicine
     Credentials: MD
      Dr. Gail Demmler-Harrison, MD, is a pediatric infectious diseases specialist, clinical virologist, and the Principal Investigator for the Houston Congenital Cytomegalovirus (CMV) Longitudinal Study. Dr Demmler is a Professor of Pediatrics at Baylor College of Medicine and Attending Physician at Texas Children's Hospital, Houston, Texas and she has studied the biology, epidemiology, diagnosis, clinical manifestations, long term effects, treatment, and prevention of CMV infections for over 30 years at these institutions. She is also author of numerous scientific publications, book chapters, and an on-line website and blog on CMV.
      ASHA DISCLOSURE:

Financial - Receives Salary for Employment from Baylor College of Medicine .   Receives Royalty options or other ownership interest for Other activities from Elsevier Publisher.   Receives Grants for Independent contractor from Centers for Disease Control.  

Nonfinancial - No relevant nonfinancial relationship exist.
Chantal Caviness - Author
Baylor School of Medicine
     Credentials: MD, MPH, PhD
      Dr. Chantal Caviness is a pediatrician and holds a PhD in Epidemiology. She is an Associate Research Director for the section of pediatric emergency medicine and guides clinical research methodology within the section. She directs the clinical research and evidence-based medicine teaching initiatives within the section. She is a Co-Investigator for the National Children’s Study, which is the largest pediatric cohort study to be conducted within the United States. She is a Co-Investigator in an Emergency Medical Services for Children (EMSC)-funded project for pediatric asthma management in the emergency department.
      ASHA DISCLOSURE:

Financial -

Nonfinancial -
Tatiana Lanzieri - Author
CDC
     Credentials: MD, MPH
      Dr. Tatiana Lanzieri, MD, MPH is a subject matter expert on congenital cytomegalovirus in the Herpesvirus Team in the Epidemiology Branch of the Division of Viral Diseases at the U.S. Centers for Disease Control and Prevention (CDC). She has been involved in epidemiologic and mathematical modeling studies of congenital and perinatal CMV infection.
      ASHA DISCLOSURE:

Financial - No relevant financial relationship exist.

Nonfinancial - No relevant nonfinancial relationship exist.
Glen Abedi - Author
CDC
     Credentials: MPH
      Glen Abedi is an epidemiologist at the CDC. He works on respiratory diseases and congenital cytomegalovirus.
      ASHA DISCLOSURE:

Financial - No relevant financial relationship exist.

Nonfinancial - No relevant nonfinancial relationship exist.
Marily Flores - Author
Baylor School of Medicine
     Credentials: MPH
      Marily Flores is an epidemiologist with the Houston Congenital CMV Longitudinal Study.
      ASHA DISCLOSURE:

Financial - No relevant financial relationship exist.

Nonfinancial - No relevant nonfinancial relationship exist.